Disintegrin and Metalloproteinase Domain-Containing Protein 17

Preferred Label : Disintegrin and Metalloproteinase Domain-Containing Protein 17;

NCIt synonyms : ADAM17; CD156b; TACE; TNF-Alpha Convertase; CD156b Antigen; TNF-Alpha-Converting Enzyme; Snake Venom-Like Protease; EC 3.4.24.86; Antigen CD156b; ADAM 17; A Disintegrin and Metalloproteinase Domain 17; Tumor Necrosis Factor-Alpha Converting Enzyme; TNF-Alpha Converting Enzyme;

NCIt definition : Disintegrin and metalloproteinase domain-containing protein 17 (824aa, 93 kDa) is encoded by the human ADAM17 gene. This protein is involved in protein cleavage.;

Details

Origin ID

C48216;

UMLS CUI

C1569773;

Automatic exact mappings (from CISMeF team)
- A disintegrin and metalloproteinase domain 17 [OMIM gene]
- ADAM metallopeptidase domain 17 [ORDO Gene]
- ADAM17 Protein [MeSH Descriptor]
- ADAM17 Protein [MeSH concept]
False automatic mappings
- Chlorotrianisene [ICD-11 Extension code]
OMIM relation
- A disintegrin and metalloproteinase domain 17 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ADAM17 protein, human [MeSH concept]
- ADAM17 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- ADAM17 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Metallopeptidase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_biochemical_function
- ADAM Family Protein [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- ADAM Type Metalloprotease Domain [NCIt concept]
- Disintegrin Domain [NCIt concept]
- Metal Binding Site [NCIt concept]
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Metastasis and Aggressiveness Marker [NCIt concept]
gene_product_is_element_in_pathway
- Alzheimer's Disease Pathway KEGG [NCIt concept]
- ERBB4 Signaling Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
- Gamma-Secretase Mediated ErbB4 Signaling Pathway [NCIt concept]
- Nerve Growth Factor Receptor Signaling Pathway [NCIt concept]
- Notch Signaling Pathway [NCIt concept]
- Notch and Wnt Signaling Pathway [NCIt concept]
- Segmentation Clock Pathway [NCIt concept]
- TNF Receptor Family Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Proteolysis [NCIt concept]
is_target
- Aderbasib [NCIt concept]
- IMT-1012 Immunotherapeutic Vaccine [NCIt concept]
- Therapeutic Breast/Ovarian/Prostate Peptide Cancer Vaccine DPX-0907 [NCIt concept]

Keyword's position in hierarchy(ies) :

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