Tyrosine-Protein Kinase Lyn

Preferred Label : Tyrosine-Protein Kinase Lyn;

NCIt synonyms : LYN; p53 LYN; p56 LYN; p56-LYN; p53-LYN; p53Lyn; p56LYN; EC 2.7.10.2; V-yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog; Lck/Yes-Related Novel Protein Tyrosine Kinase; p53-LYN Protein;

NCIt definition : Tyrosine-protein kinase Lyn (512 aa, 59 kDa) is encoded by the human LYN gene. This protein plays a role in tyrosine phosphorylation, signal transduction and the regulation of B-cell-mediated immunity.;

Details

Origin ID

C17326;

UMLS CUI

C1442804;

OMIM relation
- Lyn protooncogene, src family tyrosine kinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- LYN protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- LYN Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- SRC Family Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- SH2 Domain [NCIt concept]
- SH3 Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Tyrosine Kinase Domain [NCIt concept]
gene_product_is_element_in_pathway
- B Cell Receptor Signaling Pathway [NCIt concept]
- BCR Immune Response Signaling Pathway [NCIt concept]
- BCR Signaling Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
- Erythropoietin Signaling Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway BioCarta [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- Long-Term Depression Pathway [NCIt concept]
- Lysophosphatidic Acid Receptor Signaling Pathway [NCIt concept]
- Mast/Stem Cell Growth Factor Receptor Signaling Pathway [NCIt concept]
- Phosphoinositide Pathway [NCIt concept]
- Platelet Aggregation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Immunoglobulin-Mediated Cell Signaling [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]
is_target
- Rebastinib [NCIt concept]
- Rebastinib Tosylate [NCIt concept]

Keyword's position in hierarchy(ies) :

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