LYN wt Allele - CISMeF

Preferred Label : LYN wt Allele;

NCIt synonyms : v-YES-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog Gene; JTK8; p53Lyn; p56Lyn; LYN Proto-Oncogene, Src Family Tyrosine Kinase wt Allele;

NCIt definition : Human LYN wild-type allele is located within 8q13 and is approximately 132 kb in length. This allele, which encodes tyrosine-protein kinase Lyn protein, plays a role in B-cell receptor signaling, Fc epsilon receptor I signaling and glycoprotein VI-mediated platelet activation. Decreased expression of the LYN gene is associated with systemic lupus erythematosus.;

GenBank Accession Number : NM_002350;

Details

Origin ID

C51122;

UMLS CUI

C1708630;

OMIM relation
- Lyn protooncogene, src family tyrosine kinase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 8: 56954926-57085685 [NCIt concept]
gene_in_chromosomal_location
- 8q13 [NCIt concept]
gene_is_element_in_pathway
- B Cell Receptor Signaling Pathway [NCIt concept]
- BCR Immune Response Signaling Pathway [NCIt concept]
- BCR Signaling Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
- Erythropoietin Signaling Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway BioCarta [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- Long-Term Depression Pathway [NCIt concept]
- Lysophosphatidic Acid Receptor Signaling Pathway [NCIt concept]
- Mast/Stem Cell Growth Factor Receptor Signaling Pathway [NCIt concept]
- Phosphoinositide Pathway [NCIt concept]
- Platelet Aggregation Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Immunoglobulin-Mediated Cell Signaling [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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