" /> Disintegrin and Metalloproteinase Domain-Containing Protein 10 - CISMeF





Preferred Label : Disintegrin and Metalloproteinase Domain-Containing Protein 10;

NCIt synonyms : Kuzbanian Protein Homolog; CD156c; EC 3.4.24.81; ADAM 10; Mammalian Disintegrin-Metalloprotease; CDw156; Antigen CD156c; ADAM10;

NCIt definition : Disintegrin and metalloproteinase domain-containing protein 10 (748 aa, 84 kDa) is encoded by the human ADAM10 gene. This protein plays a role in the mediation of proteolysis of plasma membrane proteins.;

NCIt note : Disintegrin and metalloproteinase domain-containing protein 10 cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form, mediates alpha-secretase cleavage of amyloid precursor protein and regulates notch signaling through proteolysis. Other ADAM10 substrates include heparin-binding epidermal growth-like factor, ephrin-A2, cellular prion protein and the adhesion molecule L1. (UniProt);

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
29/04/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.