MAPK14 wt Allele

Preferred Label : MAPK14 wt Allele;

NCIt synonyms : CSBP2; RK; Mitogen-Activated Protein Kinase 14 wt Allele; CSBP1; PRKM15; PRKM14; SAPK2A; p38 MAPK Gene; p38Alpha; p38; Mxi2; CSPB1; EXIP;

NCIt definition : Human MAPK14 wild-type allele is located within 6p21.3-p21.2 and is approximately 83 kb in length. This allele, which encodes mitogen-activated protein kinase 14 protein, plays a role in both the production of certain cytokines and the regulation of cellular signaling in response to environmental stress, lipopolysaccharide and pro-inflammatory cytokines.;

NCIt note : The MAPK14 gene is expressed in the brain, heart, kidneys, liver, lungs, placenta, pancreas and skeletal muscle. This gene produces four RNA transcript variants which encode distinct isoforms of mitogen-activated protein kinase 14 protein.;

GenBank Accession Number : NM_001315;

Details

Origin ID

C51219;

UMLS CUI

C1705633;

OMIM relation
- Mitogen-activated protein kinase 14 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 6p21.3-p21.2 [NCIt concept]
gene_is_element_in_pathway
- 4-1BB-Dependent Immune Response Pathway [NCIt concept]
- Amyotrophic Lateral Sclerosis Pathway [NCIt concept]
- B-Cell Immune Response Pathway [NCIt concept]
- BCR Signaling Pathway [NCIt concept]
- Bioactive Peptide Signaling Pathway [NCIt concept]
- CCR5 Signaling Pathway [NCIt concept]
- CREB Activation Signaling Pathway [NCIt concept]
- Chagas Disease Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Formyl Peptide Receptor 1 Signaling Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- Human Cytomegalovirus Infection Pathway [NCIt concept]
- IL12 Signaling Pathway [NCIt concept]
- IL1R Signaling Pathway [NCIt concept]
- Keratinocyte Differentiation Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- MAP Kinase Regulation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- Map Kinase Inactivation of SMRT Corepressor Pathway [NCIt concept]
- NFAT Pathway [NCIt concept]
- NFKB Activation Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Oxidative Stress Pathway [NCIt concept]
- Progesterone-Mediated Oocyte Maturation Pathway [NCIt concept]
- Pyk2 and Map Kinase Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
- SARS Coronavirus Protease Pathway [NCIt concept]
- Salmonella Pathway [NCIt concept]
- Shigellosis Pathway [NCIt concept]
- Skeletal Myogenesis Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- TNF Stress Related Signaling Pathway [NCIt concept]
- TSP-1 Induced Apoptosis Pathway [NCIt concept]
- Th2 Cytokine Gene Induction Pathway [NCIt concept]
- Toll-Like Receptor Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
- eIF4 Regulation Pathway [NCIt concept]
- p38 MAPK Signaling Pathway BioCarta [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Stress Response Signaling [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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