Preferred Label : Interleukin-8;
NCIt synonyms : Anionic Neutrophil Activating Peptide; Macrophage-Derived Chemotactic Factor; Neutrophil Chemotactic Factor; Monocyte-Derived Neutrophil-Activating Peptide; Monocyte-Derived Neutrophil Chemotactic Factor; Granulocyte Chemotactic Peptide Interleukin 8; IL-8; Interleukin 8; Neutrophil Activation Peptide; GCP-IL-8; NAP-1; MDNCF; Leukocyte Adhesion Inhibitor; Anionic Neutrophil-Activating Peptide; IL8; Neutrophil Activation Factor; Neutrophil-Activating Peptide 1; GCP-1; Granulocyte Chemotactic Protein 1; CXCL8; T-Cell Chemotactic Factor; Beta Endothelial Cell-Derived Neutrophil Activating Peptide; Lymphocyte Derived Neutrophil Activating Peptide; Protein 3-10C; C-X-C Motif Chemokine 8; Neutrophil-Activating Protein 1; MONAP; Beta-Thromboglobulin-Like Protein; Alveolar Macrophage Chemotactic Factor I; Lung Giant Cell Carcinoma-Derived Chemotactic Protein;
NCIt definition : Interleukin-8 (99 aa, 11 kDa) is encoded by the human CXCL8 gene. This protein is
involved in chemotaxis and neutrophil activation.;
NCIt note : Interleukin-8 is cleaved into the following seven chains: MDNCF-a (GCP/IL-8 protein
IV, IL8/NAP1 form I), Interleukin-8 ((Ala-IL-8)77, GCP/IL-8 protein II, IL-8(1-77),
IL8/NAP1 form II, MDNCF-b), IL-8(5-77), IL-8(6-77) ((Ser-IL-8)72, GCP/IL-8 protein
I, IL8/NAP1 form III, lymphocyte-derived neutrophil-activating factor, LYNAP, MDNCF-c,
neutrophil-activating factor, NAF), IL-8(7-77) (GCP/IL-8 protein V, IL8/NAP1 form
IV), IL-8(8-77) (GCP/IL-8 protein VI, IL8/NAP1 form V), and IL-8(9-77) (GCP/IL-8 protein
III; IL8/NAP1 form VI). (UniProt);
Origin ID : C20473;
UMLS CUI : C1698756;
Currated CISMeF NLP mapping
- False automatic mappings
- OMIM relation
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- gene_encodes_gene_product
- gene_product_has_associated_anatomy
- gene_product_has_biochemical_function
- gene_product_is_element_in_pathway
- gene_product_plays_role_in_biological_process
- is_target
