Hematopoiesis Pathway

Preferred Label : Hematopoiesis Pathway;

NCIt related terms : Regulation of hematopoiesis by cytokines;

Alternative definition : BIOCARTA: The process of hematopoiesis is regulated by various cytokines. The combination of cytokines stimulates the proliferation and/or differentiation of the various hematopoietic cell types. Bone marrow stromal cells are the major source of hematopoietic cytokines in the non-infectious state. In the presence of infection, cytokines produced by activated macrophages and TH cells induce hematopoietic activity. The induction by cytokines results in rapid expansion of the population of white blood cells to fight infection. (This definition may be outdated - see the DesignNote.);

NCIt note : The BIOCARTA Definition (ALT_DEFINITION) for this pathway concept was provided by BioCarta. This property was not created by, nor is it maintained by the NCI Thesaurus staff. Additionally, BioCarta is no longer updating its pathway data; thus, the BIOCARTA Definition might be outdated or inaccurate. Please see the Terms and Conditions for Use at http://www.biocarta.com/.;

Biocarta ID : h_stemPathway;

Details

Origin ID

C39240;

UMLS CUI

C1512384;

Semantic type(s)
- Molecular Function [UMLS semantic type]
has_gene_product_element
- Erythropoietin [NCIt concept]
- Granulocyte Colony-Stimulating Factor [NCIt concept]
- Granulocyte-Macrophage Colony-Stimulating Factor [NCIt concept]
- Interleukin-11 [NCIt concept]
- Interleukin-2 [NCIt concept]
- Interleukin-3 [NCIt concept]
- Interleukin-4 [NCIt concept]
- Interleukin-5 [NCIt concept]
- Interleukin-6 [NCIt concept]
- Interleukin-7 [NCIt concept]
- Interleukin-8 [NCIt concept]
- Interleukin-9 [NCIt concept]
- Macrophage Colony-Stimulating Factor 1 [NCIt concept]
- T-Cell Surface Glycoprotein CD4 [NCIt concept]
- T-Cell Surface Glycoprotein CD8 Alpha Chain [NCIt concept]
pathway_has_gene_element
- CD4 wt Allele [NCIt concept]
- CSF1 wt Allele [NCIt concept]
- CSF2 wt Allele [NCIt concept]
- CSF3 wt Allele [NCIt concept]
- CXCL8 wt Allele [NCIt concept]
- EPO wt Allele [NCIt concept]
- IL11 wt Allele [NCIt concept]
- IL2 wt Allele [NCIt concept]
- IL3 wt Allele [NCIt concept]
- IL4 wt Allele [NCIt concept]
- IL5 wt Allele [NCIt concept]
- IL6 wt Allele [NCIt concept]
- IL7 wt Allele [NCIt concept]
- IL9 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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