Interleukin-3 - CISMeF

Preferred Label : Interleukin-3;

NCIt synonyms : Erythrocyte Burst-Promoting Factor; Multipotential Colony-Stimulating Factor; Eosinophil-Mast Cell Growth-Factor; P-Cell-Stimulating Factor; MULTI-CSF; MCGF; P-Cell Stimulating Factor; IL3 Protein; Multilineage-Colony-Stimulating Factor; Mast-Cell Growth Factor; Mast-Cell Colony-Stimulating Factor; IL3; Colony-Stimulating Factor 2 Alpha; Interleukin 3 Precursor; Interleukin 3; Mast Cell Growth Factor;

NCIt related terms : IL-3;

NCIt definition : Interleukin-3 (152 aa, 17 kDa) is encoded by the human IL3 gene. This protein plays a role in neurotrophic activity and the proliferation of several types of hematopoietic lineage cells.;

Alternative definition : NCI-GLOSS: One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-3 is made mainly by a type of T lymphocyte. It increases the number of blood cells made by the bone marrow. IL-3 made in the laboratory is used as a biological response modifier to boost the immune system in cancer therapy. IL-3 is a type of cytokine.;

Codes from synonyms : CDR0000044419; CDR0000045150;

Details

Origin ID

C20439;

UMLS CUI

C1701061;

Automatic exact mappings (from CISMeF team)
- Interleukin 3 [OMIM gene]
- KIT ligand [ORDO Gene]
- KIT ligand [HGNC gene]
- Kit ligand [OMIM gene]
- interleukin 3 [HGNC gene]
- interleukin-3 receptor binding [GO term]
- stem cell factor [MeSH Descriptor]
- stem cell factor [MeSH concept]
False automatic mappings
- Interleukin-3 (substance) [SNOMED CT concept]
OMIM relation
- Interleukin 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- IL3 protein, human [MeSH concept]
- IL3 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- Hematopoietic Factor Gene [NCIt concept]
- IL3 Gene [NCIt concept]
- Interleukin Gene [NCIt concept]
gene_product_has_associated_anatomy
- Bone Marrow [NCIt concept]
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Growth Factor [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Allergy Chemokine Network Pathway [NCIt concept]
- Apoptosis Pathway [NCIt concept]
- Asthma Pathway [NCIt concept]
- BAD Regulation Pathway [NCIt concept]
- Calcineurin-Regulated NFAT-Dependent Transcription Pathway [NCIt concept]
- Calcium Signaling in the CD4+ TCR Pathway [NCIt concept]
- Cytokine Network Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Dendritic Cell Pathway [NCIt concept]
- Erythrocyte Differentiation Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Hematopoiesis Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- IL17 Signaling Pathway [NCIt concept]
- IL3 Signaling Pathway [NCIt concept]
- Inflammatory Response Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Hematopoietic Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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