Granulocyte Colony-Stimulating Factor

Preferred Label : Granulocyte Colony-Stimulating Factor;

NCIt synonyms : G CSF; Pluripoietin; Colony Stimulating Factor 3; Colony-Stimulating Factor (Granulocyte); Granulocyte Colony Stimulating Factor; CSF3; G-CSF; Colony-Stimulating Factor 3; Colony Stimulating Factor-3; GCSF;

NCIt definition : Granulocyte colony-stimulating factor (207 aa, 22 kDa) is encoded by the human CSF3 gene. This protein is involved in the regulation of the production, differentiation, and function of granulocytes.;

Alternative definition : NCI-GLOSS: A colony-stimulating factor that stimulates the production of neutrophils (a type of white blood cell). It is a cytokine that is a type of hematopoietic (blood-forming) agent.;

Codes from synonyms : CDR0000046749; CDR0000046075;

Details

Origin ID

C26078;

UMLS CUI

C5441740;

OMIM relation
- Colony-stimulating factor 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
gene_encodes_gene_product
- CSF3 Gene [NCIt concept]
- Colony-Stimulating Factor Gene [NCIt concept]
- Cytokine Gene [NCIt concept]
- Hematopoietic Factor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Bone Marrow [NCIt concept]
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Growth Factor [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Erythrocyte Differentiation Pathway [NCIt concept]
- Granulocyte Adhesion Pathway [NCIt concept]
- Hematopoiesis Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- IL17 Signaling Pathway [NCIt concept]
- Inflammatory Response Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Granulopoiesis [NCIt concept]
- Hematopoietic Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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