Preferred Label : Filgrastim;
NCIt synonyms : Recombinant Methionyl Human Granulocyte Colony Stimulating Factor; G-CSF; r-metHuG-CSF; rG-CSF; Filgrastim-aafi; Filgrastim Biosimilar Filgrastim-sndz; Filgrastim Biosimilar Tbo-filgrastim; Filgrastim XM02;
NCIt related terms : Releuko; Tbo-filgrastim; Filgrastim-sndz; Filgrastim-ayow;
NCIt definition : A recombinant, non-glycosylated cytokine which is chemically identical to or similar
to the endogenous cytokine human granulocyte colony-stimulating factor (G-CSF) isoform
B, with immunomodulating activity. Filgrastim binds to and activates G-CSF receptors
with the same biological activity and stability as the endogenous cytokine, thereby
controlling the production, differentiation, and function of neutrophilic granulocyte
progenitors.;
Alternative definition : NCI-GLOSS: A colony-stimulating factor that stimulates the production of neutrophils
(a type of white blood cell). It is a cytokine that is a type of hematopoietic (blood-forming)
agent.;
UNII : PVI5M0M1GW;
CAS number : 121181-53-1;
Drug name : Neupogen; Tevagrastim; Nivestym; Releuko; Granix; Zarxio; Neutroval; Nivestim;
Molecule name : XM02;
Codes from synonyms : CDR0000045332; 219; 66258; 480; 220; 120189;
Origin ID : C1474;
UMLS CUI : C0210630;
CISMeF manual mappings
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- chemical_or_drug_affects_cell_type_or_tissue
- chemical_or_drug_affects_gene_product
- chemical_or_drug_has_mechanism_of_action
- chemical_or_drug_has_physiologic_effect
- concept_is_in_subset
- has_target
- is_component_of_chemotherapy_regimen
https://pgtmsite.files.wordpress.com/2024/01/ad_filgrastim-ped_rapport-pgtm_final_v1.1.pdf
2018
Canada
drug information
Pediatric
Analysis
Filgrastim
Analyzed
Pediatric
Use
Filgrastim
pediatrics
quebec
hospitals, university
Description
pediatrician
Identifier
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https://pgtmsite.files.wordpress.com/2024/01/protocole_ad_filgrastim-amende_01jun16_maj_28mai2018.pdf
2018
Canada
drug information
Filgrastim
quebec
hospitals, university
Use
Filgrastim
---
https://pgtmsite.files.wordpress.com/2024/01/filgrastim_ad_rapport-pgtm_adulte_20180222_finale.pdf
2018
Canada
drug information
adult
Filgrastim
Analysis
quebec
Legal Adult
Identifier
Description
hospitals, university
Use
adulthood
Filgrastim
Analyzed
---
https://pgtmsite.files.wordpress.com/2024/01/filgastrim_es_facteur-de-croissances-des-granulocytes_biosimilaires_web_31aout2017.pdf
2017
Canada
drug information
Granulocyte Count
Granulocyte Colony-Stimulating Factor
OMD Gene
Doctor of Medicine
GDC Method of Diagnosis Terminology
cesium fluoride
Osteomodulin
Granulocyte
Granulocyte Colony-Stimulating Factor
Murine Granulocytes
GDC Metastasis at Diagnosis Terminology
growth factors
granulocytes
colony-stimulating factor, granulocytic
Filgrastim
Moldova, Republic of
acute myeloid leukemia
Maryland
Filgrastim
Growth Factor
growth factor, nos
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