Interleukin-11

Preferred Label : Interleukin-11;

NCIt synonyms : Interleukin 11; IL11; Adipogenesis Inhibitory Factor; AGIF;

NCIt related terms : IL-11;

NCIt definition : Interleukin-11 (199 aa, 21 kDa) is encoded by the human IL11 gene. This protein is involved in the proliferation of hematopoietic cells and the induction of platelet production.;

Alternative definition : NCI-GLOSS: One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-11 is made by support cells in the bone marrow. It causes the growth of several types of blood cells. Oprelvekin (interleukin-11 made in the laboratory) is used as a biological response modifier to increase the number of platelets, especially in patients receiving chemotherapy for cancer. Interleukin-11 is a type of cytokine.;

Codes from synonyms : CDR0000044417; CDR0000045463;

Details

Origin ID

C20513;

UMLS CUI

C1699803;

Currated CISMeF NLP mapping
- Interleukin-11 [MeSH Descriptor]
- Interleukin-11 [MeSH concept]
- interleukin-11 [SNOMED Notion]
False automatic mappings
- Interleukin-11 (substance) [SNOMED CT concept]
OMIM relation
- Interleukin 11 [OMIM gene]
See also inter- (CISMeF)
- Product containing interleukin-11 (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- IL11 protein, human [MeSH concept]
- IL11 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- IL11 Gene [NCIt concept]
- Interleukin Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Hematopoiesis Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- Inflammatory Response Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- B Cell Proliferation [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
is_target
- Anti-IL-11 Monoclonal Antibody 9MW3811 [NCIt concept]

Keyword's position in hierarchy(ies) :

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