Interleukin-5 - CISMeF

Preferred Label : Interleukin-5;

NCIt synonyms : TRF; B-Cell Differentiation Factor I; T-Cell Replacing Factor; Eosinophil Differentiation Factor; Interleukin 5; EDF; B-Cell Growth Factor-II; BCGF-II; Interleukin 5 Precursor; Eo-CSF; IL5; B Cell Differentiation Factor I;

NCIt related terms : IL-5;

NCIt definition : Interleukin-5 (134 aa, 15 kDa) is encoded by the human IL5 gene. This protein plays a role in the growth and differentiation of both B-cells and eosinophils.;

Alternative definition : NCI-GLOSS: One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-5 is made mainly by some T lymphocytes. It causes B lymphocytes to make more antibodies and increases the number of eosinophils. IL-5 made in the laboratory is used as a biological response modifier to boost the immune system in cancer therapy. It is a type of cytokine.;

Codes from synonyms : CDR0000682071; CDR0000557292;

Details

Origin ID

C20509;

UMLS CUI

C1702088;

Currated CISMeF NLP mapping
- Interleukin 5 [LOINC component]
- Interleukin-5 [FMA entity]
- Interleukin-5 [MeSH Descriptor]
- Interleukin-5 [MeSH concept]
- interleukin-5 [SNOMED Notion]
False automatic mappings
- Interleukin-5 (substance) [SNOMED CT concept]
OMIM relation
- Interleukin 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- IL5 protein, human [MeSH concept]
- IL5 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- Hematopoietic Factor Gene [NCIt concept]
- IL5 Gene [NCIt concept]
- Interleukin Gene [NCIt concept]
gene_product_has_associated_anatomy
- Bone Marrow [NCIt concept]
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Growth Factor [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Allergy Chemokine Network Pathway [NCIt concept]
- Allograft Rejection Pathway [NCIt concept]
- Asthma Pathway [NCIt concept]
- Autoimmune Thyroid Disease Pathway [NCIt concept]
- Calcineurin-Regulated NFAT-Dependent Transcription Pathway [NCIt concept]
- Cytokine Network Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Dendritic Cell Pathway [NCIt concept]
- Glucocorticoid Receptor Regulatory Network [NCIt concept]
- Hematopoiesis Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- IL4-Mediated Signaling Pathway [NCIt concept]
- IL5 Signaling Pathway [NCIt concept]
- Inflammatory Response Pathway [NCIt concept]
- Intestinal IgA Production Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Polarization Pathway [NCIt concept]
- Th2 Cytokine Gene Induction Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Asthma [NCIt concept]
- Idiopathic Hypereosinophilic Syndrome [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Hematopoietic Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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