NCIt definition : A synthetic peptide that mimics the anti-angiogenic activity of the endogenous protein
thrombospondin-1 (TSP-1). ABT-510 inhibits the actions of several pro-angiogenic growth
factors important to tumor neovascularization; these pro-angiogenic growth factors
include vascular endothelial growth factor (VEGF), basic fibroblast growth factor
(bFGF)), hepatocyte growth factor (HGF), and interleukin 8 (IL-8). (NCI04);
Alternative definition : NCI-GLOSS: A substance being studied in the treatment of cancer. It is a type of angiogenesis
inhibitor.;