Fibroblast Growth Factor 2

Preferred Label : Fibroblast Growth Factor 2;

NCIt synonyms : bFGF; Heparin-Binding Growth Factor 2; Prostatropin; Basic Fibroblast Growth Factor; FGF2; FGF-2; HBGF-2; Fibroblast Growth Factor-2;

NCIt definition : Fibroblast growth factor 2 (288 aa, 31 kDa) is encoded by the human FGF2 gene. This protein plays a role in the regulation of cell proliferation, angiogenesis, and limb and nervous system development.;

Details

Origin ID

C20547;

UMLS CUI

C3887569;

Automatic exact mappings (from CISMeF team)
- Fibroblast growth factor 2 [LOINC component]
OMIM relation
- Fibroblast growth factor 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- FGF2 Gene [NCIt concept]
- Fibroblast Growth Factor Gene Family [NCIt concept]
- Growth Factor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Heparin Binding Growth Factor [NCIt concept]
gene_product_is_biomarker_type
- Proliferation Marker [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Angiopoietin-1 Receptor Signaling Pathway [NCIt concept]
- FGF Signaling Pathway [NCIt concept]
- Glypican 1 Signaling Pathway [NCIt concept]
- Integrin Angiogenesis Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- Melanoma Pathway [NCIt concept]
- NFAT Pathway [NCIt concept]
- Syndecan-4-Mediated Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cell Survival [NCIt concept]
- Heparin Binding [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Limb Development [NCIt concept]
- Pattern Formation [NCIt concept]
- Receptor Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]
- Wound Repair [NCIt concept]
is_target
- Lenalidomide [NCIt concept]
- TSP-1 Mimetic ABT-510 [NCIt concept]

Keyword's position in hierarchy(ies) :

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