" /> Lenalidomide - CISMeF





Preferred Label : Lenalidomide;

NCIt synonyms : 3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione;

NCIt related terms : Revlimid; CC-5013;

NCIt definition : A thalidomide analog with potential antineoplastic activity. Lenalidomide inhibits TNF-alpha production, stimulates T cells, reduces serum levels of the cytokines vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), and inhibits angiogenesis. This agent also promotes G1 cell cycle arrest and apoptosis of malignant cells.;

Alternative definition : NCI-GLOSS: A drug that is similar to thalidomide, and is used to treat multiple myeloma and certain types of anemia. It is also being studied in the treatment of other types of cancer. Lenalidomide belongs to the family of drugs called angiogenesis inhibitors.;

UNII : F0P408N6V4;

InChIKey : GOTYRUGSSMKFNF-UHFFFAOYSA-N;

CAS number : 191732-72-6;

Drug name : Revlimid;

Molecule name : CC-5013; CDC 501; CC 5013;

Chemical formula : C13H13N3O3;

NSC code : 703813;

ChEBI ID : CHEBI:63791;

Codes from synonyms : CDR0000045081; CDR0000507521; CDR0000393761; 299;

PubMed : 16085014;

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08/05/2025


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