Limb Development

Preferred Label : Limb Development;

NCIt definition : Interdependent positional signaling by the apical ectodermal ridge, the posterior mesenchyme zone of polarizing activity, and the non ridge ectoderm coordinate limb bud outgrowth and patterning, Limb Development, by migrated lateral plate mesoderm and somite cells. Proximal-distal differentiating mesenchymal cells condense to form the limb skeletal primordia.;

Details

Origin ID

C19946;

UMLS CUI

C1517884;

Currated CISMeF NLP mapping
- limb development [GO term]
Semantic type(s)
- Organ or Tissue Function [UMLS semantic type]
UMLS correspondences (same concept)
- limb development [GO term]
biological_process_has_result_anatomy
- Limb [NCIt concept]
- Organ [NCIt concept]
biological_process_involves_gene_product
- 26S Proteasome Complex Subunit SEM1 [NCIt concept]
- CD44 Antigen [NCIt concept]
- Cartilage Oligomeric Matrix Protein [NCIt concept]
- Exostosin-1 [NCIt concept]
- Exostosin-2 [NCIt concept]
- Fibroblast Growth Factor 2 [NCIt concept]
- Fibroblast Growth Factor 4 [NCIt concept]
- Gremlin-1 [NCIt concept]
- Homeobox Protein Aristaless-Like 4 [NCIt concept]
- Homeobox Protein SIX1 [NCIt concept]
- LIM Homeobox Transcription Factor 1 Beta [NCIt concept]
- Nipped-B-Like Protein [NCIt concept]
- Protein Jagged-2 [NCIt concept]
- Protein Wnt-7a [NCIt concept]
- R-Spondin-2 [NCIt concept]
- Sal-Like Protein 4 [NCIt concept]
- T-Box Transcription Factor TBX3 [NCIt concept]
- T-Box Transcription Factor TBX4 [NCIt concept]
- T-Box Transcription Factor TBX5 [NCIt concept]
- Tumor Protein 63 [NCIt concept]
- Zinc Finger Protein GLI3 [NCIt concept]
biological_process_is_part_of_process
- Maturation [NCIt concept]
process_involves_gene
- ALX4 Gene [NCIt concept]
- ALX4 wt Allele [NCIt concept]
- CD44 Gene [NCIt concept]
- CD44 wt Allele [NCIt concept]
- COMP Gene [NCIt concept]
- COMP wt Allele [NCIt concept]
- EXT1 Gene [NCIt concept]
- EXT1 wt Allele [NCIt concept]
- EXT2 Gene [NCIt concept]
- EXT2 wt Allele [NCIt concept]
- FBXW4 Gene [NCIt concept]
- FBXW4 wt Allele [NCIt concept]
- FGF2 Gene [NCIt concept]
- FGF2 wt Allele [NCIt concept]
- FGF4 Gene [NCIt concept]
- FGF4 wt Allele [NCIt concept]
- GLI3 Gene [NCIt concept]
- GLI3 wt Allele [NCIt concept]
- GREM1 Gene [NCIt concept]
- GREM1 wt Allele [NCIt concept]
- JAG2 Gene [NCIt concept]
- JAG2 wt Allele [NCIt concept]
- LMX1B Gene [NCIt concept]
- LMX1B wt Allele [NCIt concept]
- NIPBL Gene [NCIt concept]
- NIPBL wt Allele [NCIt concept]
- RSPO2 Gene [NCIt concept]
- RSPO2 wt Allele [NCIt concept]
- SALL4 Gene [NCIt concept]
- SALL4 wt Allele [NCIt concept]
- SEM1 Gene [NCIt concept]
- SEM1 wt Allele [NCIt concept]
- SIX1 Gene [NCIt concept]
- SIX1 wt Allele [NCIt concept]
- TBX3 Gene [NCIt concept]
- TBX3 wt Allele [NCIt concept]
- TBX4 Gene [NCIt concept]
- TBX4 wt Allele [NCIt concept]
- TBX5 Gene [NCIt concept]
- TBX5 wt Allele [NCIt concept]
- TP63 Gene [NCIt concept]
- TP63 wt Allele [NCIt concept]
- WNT7A Gene [NCIt concept]
- WNT7A wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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