Gremlin-1 - CISMeF

Preferred Label : Gremlin-1;

NCIt synonyms : IHG-2; Gremlin 1; Increased In High Glucose-2; Down-Regulated in Mos-Transformed Cells Protein; Cell Proliferation-Inducing Gene 2 Protein; DAN Domain Family Member 2; GREM1; Increased In High Glucose Protein 2; Cysteine Knot Superfamily 1, BMP Antagonist 1;

NCIt definition : Gremlin-1 (184 aa, 21 kDa) is encoded by the human GREM1 gene. This protein is involved in the modulation of signaling by bone morphogenetic proteins.;

Details

Origin ID

C152001;

UMLS CUI

C1438932;

Automatic exact mappings (from CISMeF team)
- Gremlin 1, dan family bmp antagonist [OMIM gene]
- gremlin 1, DAN family BMP antagonist [ORDO Gene]
OMIM relation
- Gremlin 1, dan family bmp antagonist [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- GREM1 protein, human [MeSH concept]
- GREM1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- GREM1 Gene [NCIt concept]
gene_product_expressed_in_tissue
- Brain [NCIt concept]
- Intestine [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_is_element_in_pathway
- BMP Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Limb Development [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Anti-gremlin-1 Monoclonal Antibody TST003 [NCIt concept]
- Ginisortamab [NCIt concept]

Keyword's position in hierarchy(ies) :

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