Preferred Label : CD44 wt Allele;
NCIt synonyms : Pgp1; MDU3; MDU2; ECMR-III; MIC4; LHR; CD44 Antigen (Homing Function and Indian Blood Group System) Gene; HCELL; MC56; CD44 Molecule (Indian Blood Group) wt Allele; CSPG8; HUTCH-I; IN; CDW44;
NCIt definition : Human CD44 wild-type allele is located within 11p13 and is approximately 94 kb in
length. This allele, which encodes CD44 antigen Immunoprotein, plays a role in cell-cell
interactions, cell adhesion, migration and several cellular functions.;
NCIt note : CD44 Antigen, an acidic sulfated glycosylated integral membrane hyaluronate receptor
that mediates cell-matrix adhesion, lymphocyte binding to endothelia, lymphocyte activation,
macrophage activation, motility, lymph node homing, and immune cell cytokine release.
CD44 also functions in a growth factor presentation mechanism necessary for limb development.;
GenBank Accession Number : NM_000610;
Origin ID : C51123;
UMLS CUI : C1707101;
OMIM relation
- Semantic type(s)
- concept_is_in_subset
- gene_found_in_organism
- gene_has_abnormality
- gene_has_physical_location
- gene_in_chromosomal_location
- gene_is_element_in_pathway
- gene_plays_role_in_process
