GREM1 wt Allele

Preferred Label : GREM1 wt Allele;

NCIt synonyms : IHG-2; Cell Proliferation-Inducing Gene 2; CRCS4; MPSH; GREMLIN; DRM; Gremlin 1, Cysteine Knot Superfamily, Homolog Gene; CRAC1; CKTSF1B1; PIG2; Cystine Knot Superfamily 1, BMP Antagonist 1 Gene; HMPS; DUP15q; Gremlin 1, Cysteine Knot Superfamily, Homolog (Xenopus laevis) Gene; C15DUPq; Gremlin 1 Homolog, Cysteine Knot Superfamily Gene; DAND2; Gremlin 1, DAN Family BMP Antagonist wt Allele; HMPS1; Colorectal Adenoma and Carcinoma 1 Gene;

NCIt definition : Human GREM1 wild-type allele is located in the vicinity of 15q13.3 and is approximately 27 kb in length. This allele, which encodes gremlin-1 protein, plays a role in antagonizing bone morphogenetic protein signaling pathways. Mutation of the gene is associated with hereditary mixed polyposis syndrome 1.;

NCI Metathesaurus CUI : CL553221;

GenBank Accession Number : NM_013372;

Details

Origin ID

C152000;

UMLS CUI

C4723888;

Automatic exact mappings (from CISMeF team)
- Gremlin 1, dan family bmp antagonist [OMIM gene]
- Hereditary mixed polyposis syndrome [ORDO Disease]
- Myopathy, myofibrillar, 1 [OMIM Phenotype]
- Polyposis syndrome, hereditary mixed, 1 [OMIM Phenotype]
- gremlin 1, DAN family BMP antagonist [ORDO Gene]
- guanidinoacetate N-methyltransferase [ORDO Gene]
- hereditary mixed polyposis syndrome [DO Concept]
- hereditary mixed polyposis syndrome 1 [DO Concept]
- retinal detachment [MeSH Descriptor]
OMIM relation
- Gremlin 1, dan family bmp antagonist [OMIM gene]
See also inter- (CISMeF)
- Hereditary mixed polyposis syndrome [ICD-11 More detail]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- BMP Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Limb Development [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]

Keyword's position in hierarchy(ies) :

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