Vascular Endothelial Growth Factor Family

Preferred Label : Vascular Endothelial Growth Factor Family;

NCIt synonyms : VEGF; Vascular Endothelial Growth Factor; VEGF Family;

NCIt definition : A sub-family of the cysteine knot platelet-derived growth factor family. Members of the vascular endothelial growth factor (VEGF) family play a role in the promotion of embryonic vasculogenesis and the stimulation of angiogenesis during physiologic and pathologic processes.;

NCIt note : There are five members of the VEGF family expressed in mammals: VEGF-A, placenta growth factor (PGF), VEGF-B, VEGF-C and VEGF-D.;

Details

Origin ID

C129646;

UMLS CUI

C1256770;

Automatic exact mappings (from CISMeF team)
- Vascular endothelial growth factor [LOINC component]
- Vascular endothelial growth factor (substance) [SNOMED CT concept]
- Vascular endothelial growth factor A [LOINC component]
- Vascular endothelial growth factor a [OMIM gene]
- vascular endothelial growth factor A [MeSH concept]
- vascular endothelial growth factor A [HGNC gene]
- vascular endothelial growth factor a [MeSH Descriptor]
- vascular endothelial growth factor receptor binding [GO term]
- vascular endothelial growth factors [MeSH Descriptor]
- vascular endothelial growth factors [MeSH concept]
Biochemical function of gene products
- PGF Gene Product [NCIt concept]
- Placenta Growth Factor [NCIt concept]
- Placenta Growth Factor Isoform 1 [NCIt concept]
- VEGFA Gene Product [NCIt concept]
- Vascular Endothelial Growth Factor A [NCIt concept]
- Vascular Endothelial Growth Factor A 165 Isoform [NCIt concept]
- Vascular Endothelial Growth Factor B [NCIt concept]
- Vascular Endothelial Growth Factor C [NCIt concept]
- Vascular Endothelial Growth Factor D [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- vascular endothelial growth factors [MeSH Descriptor]
- vascular endothelial growth factors [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_biochemical_function
- Growth Factor [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Wound Repair [NCIt concept]
is_target
- Anti-KSP/Anti-VEGF siRNAs ALN-VSP02 [NCIt concept]
- Anti-PD-1/Anti-VEGF Bispecific Antibody JS207 [NCIt concept]
- Anti-PD-L1/Anti-VEGF Bispecific Antibody Fusion Protein B1962 [NCIt concept]
- Anti-PD-L1/Anti-VEGF-A Bispecific Antibody PM8002 [NCIt concept]
- Anti-VEGF/ANG2 Nanobody BI 836880 [NCIt concept]
- Anti-VEGF/TGF-beta Bispecific Antibody Fusion Protein ZGGS18 [NCIt concept]
- Anti-c-Met/EGFR/VEGF Trispecific Antibody TAVO412 [NCIt concept]
- Axitinib [NCIt concept]
- Emvododstat [NCIt concept]
- Ivonescimab [NCIt concept]
- TSP-1 Mimetic ABT-510 [NCIt concept]

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