Placenta Growth Factor Isoform 1

Preferred Label : Placenta Growth Factor Isoform 1;

NCIt synonyms : PLGF1; Isoform PlGF-1; Placental Growth Factor 1 Isoform; PlGF-131; PLGF-1; Placental Growth Factor Isoform 1;

NCIt definition : Placenta growth factor isoform 1 (149 aa, 17 kDa) is encoded by the human PGF gene. This protein may be involved in the positive regulation of endothelial cell growth.;

NCIt note : PlGF-1 is expressed in the colon and in mammary carcinomas. This isoform does not contain a heparin binding domain. (UniProt);

NCI Metathesaurus CUI : CL504709;

Details

Origin ID

C126117;

UMLS CUI

C4288392;

OMIM relation
- Placental growth factor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Growth Factor Gene [NCIt concept]
- PGF Gene [NCIt concept]
gene_product_expressed_in_tissue
- Colon [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Vascular Endothelial Growth Factor Family [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Receptor Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
is_target
- Conbercept [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients