Preferred Label : Conbercept;
NCIt definition : A recombinant, soluble, vascular endothelial growth factor receptor (VEGFR) protein
composed of the second immunoglobulin (Ig) domain of VEGFR-1, the third and fourth
Ig domains of VEGFR-2, and the constant region (Fc) of human immunoglobulin G1 (IgG1)
with potential anti-angiogenic activities. Upon intravitreal injection, conbercept,
functioning as a soluble decoy receptor, binds with high affinity to all VEGF-A isoforms,
VEGF-B, as well as placenta growth factor (PlGF)-1 and PlGF-2. This prevents the binding
of these growth factors to their endogenous receptors, potentially inhibiting angiogenesis
and tumor cell growth.;
UNII : 1P05PW62F3;
CAS number : 1227158-72-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1227158-72-6
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;
Molecule name : KH 902; KH-902; FP 3; FP-3; KH-903; KH 903;
NCI Metathesaurus CUI : CL973317;
Origin ID : C162879;
UMLS CUI : C5201155;
CISMeF manual mappings
- Currated CISMeF NLP mapping
- Semantic type(s)
- concept_is_in_subset
- has_target
