Axitinib - CISMeF

Preferred Label : Axitinib;

NCIt synonyms : N-methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide;

NCIt related terms : AG-013736;

NCIt definition : An orally bioavailable tyrosine kinase inhibitor. Axitinib inhibits the proangiogenic cytokines vascular endothelial growth factor (VEGF) and platelet-derived growth factor receptor (PDGF), thereby exerting an anti-angiogenic effect.;

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called angiogenesis inhibitors and protein tyrosine kinase inhibitors.;

UNII : C9LVQ0YUXG;

InChIKey : RITAVMQDGBJQJZ-FMIVXFBMSA-N;

CAS number : 319460-85-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 319460-85-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Inlyta;

Molecule name : AG-013736;

Chemical formula : C22H18N4OS;

Codes from synonyms : CDR0000538635; CDR0000367435; 55;

Details

Origin ID

C38718;

UMLS CUI

C1700874;

Automatic exact mappings (from CISMeF team)
- Axitinib [ICD-11 Extension code]
- axitinib [ATC Code]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Axitinib [MeSH Descriptor]
- Axitinib (substance) [SNOMED CT concept]
- Product containing axitinib (medicinal product) [SNOMED CT concept]
- axitinib [International Nonproprietary Name]
- axitinib [Substance BNPC]
- axitinib [ATC Code]
- axitinib [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Platelet-Derived Growth Factor Receptor [NCIt concept]
- Vascular Endothelial Growth Factor Family [NCIt concept]
is_component_of_chemotherapy_regimen
- Avelumab/Axitinib Regimen [NCIt concept]
- Axitinib Regimen [NCIt concept]
- Axitinib/Pembrolizumab Regimen [NCIt concept]

Keyword's position in hierarchy(ies) :

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