Platelet-Derived Growth Factor Receptor

Preferred Label : Platelet-Derived Growth Factor Receptor;

NCIt synonyms : PDGFR; PDGF Receptor;

NCIt definition : A cell surface protein that has tyrosine-kinase activity. This receptor specifically binds to platelet derived growth factor, and its analogs and antagonists. Ligand binding causes homodimerization or heterodimerization, resulting in receptor activation.;

Details

Origin ID

C17322;

UMLS CUI

C0071253;

Currated CISMeF NLP mapping
- receptors, Platelet-Derived growth factor [MeSH concept]
- receptors, platelet-derived growth factor [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- Platelet-derived growth factor receptor [LOINC component]
- receptors, Platelet-Derived growth factor [MeSH concept]
- receptors, platelet-derived growth factor [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_affected_by_chemical_or_drug
- Crenolanib [NCIt concept]
- Crenolanib Besylate [NCIt concept]
- Orantinib [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Receptor [NCIt concept]
- Receptor Tyrosine Kinase [NCIt concept]
gene_product_has_chemical_classification
- Cell Surface Receptor [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Receptor Signaling [NCIt concept]
is_target
- Axitinib [NCIt concept]
- Crenolanib [NCIt concept]
- Crenolanib Besylate [NCIt concept]
- DDR1-2/VEGFR2-3/PDGFRalpha-beta Inhibitor ICP-033 [NCIt concept]
- Dovitinib [NCIt concept]
- Dovitinib Lactate [NCIt concept]
- Dovitinib Lactate Anhydrous [NCIt concept]
- Fluorine F 18 Dasatinib [NCIt concept]
- Ibcasertib [NCIt concept]
- Ilorasertib [NCIt concept]
- Imatinib [NCIt concept]
- Imatinib Mesylate [NCIt concept]
- Linifanib [NCIt concept]
- Masitinib Mesylate [NCIt concept]
- Midostaurin [NCIt concept]
- Motesanib Diphosphate [NCIt concept]
- Nintedanib [NCIt concept]
- Nintedanib Esylate [NCIt concept]
- Pazopanib [NCIt concept]
- Pazopanib Hydrochloride [NCIt concept]
- Quizartinib [NCIt concept]
- Regorafenib [NCIt concept]
- Regorafenib Hydrate [NCIt concept]
- Sunitinib [NCIt concept]
- Sunitinib Malate [NCIt concept]
- Suramin [NCIt concept]
- Suramin Sodium [NCIt concept]
- VEGFR/PDGFR Tyrosine Kinase Inhibitor TAK-593 [NCIt concept]
- VEGFR2/PDGFR/c-Kit/Flt-3 Inhibitor SU014813 [NCIt concept]
- Vorolanib [NCIt concept]

Keyword's position in hierarchy(ies) :

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