Preferred Label : Ibcasertib;
NCIt synonyms : Chiauranib;
NCIt definition : An orally available, small molecule inhibitor of select serine-threonine kinases,
including aurora kinase B (aurora B), vascular endothelial growth factor receptors
(VEGFRs), stem cell factor receptor (c-KIT), and platelet-derived growth factor receptors
(PDGFRs), with potential antineoplastic activity. Upon oral administration, ibcasertib
binds to and inhibits the activity of aurora B, VEGFRs, c-kit and PDGFRs, which may
result in a decrease in the proliferation of tumor cells that overexpress these kinases.
These kinases are overexpressed by a variety of cancer cell types.;
UNII : F40IRN5981;
CAS number : 1256349-48-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1256349-48-0
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;
Molecule name : CS2164;
NCI Metathesaurus CUI : CL473304;
Origin ID : C115970;
UMLS CUI : C3899686;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_target
