NCIt definition : The orally bioavailable mesylate salt of masatinib, a multi-targeted protein tyrosine
kinase inhibitor with potential antineoplastic activity. Masitinib selectively binds
to and inhibits both the wild-type and mutated forms of the stem cell factor receptor
(c-Kit; SCFR); platelet-derived growth factor receptor (PDGFR); fibroblast growth
factor receptor 3 (FGFR3); and, to a lesser extent, focal adhesion kinase (FAK). As
a consequence, tumor cell proliferation may be inhibited in cancer cell types that
overexpress these receptor tyrosine kinases (RTKs).;
UNII : ZK89EG3A18;
CAS number : 1048007-93-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1048007-93-7
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