VEGFR/PDGFR Tyrosine Kinase Inhibitor TAK-593

Preferred Label : VEGFR/PDGFR Tyrosine Kinase Inhibitor TAK-593;

NCIt synonyms : VEGFR PDGFR Tyrosine Kinase Inhibitor TAK-593;

NCIt related terms : TAK-593;

NCIt definition : An oral formulation containing a small-molecule receptor tyrosine kinase inhibitor of both vascular endothelial growth factor receptor (VEGFR) and platelet-derived growth factor receptor (PDGFR) with potential antineoplastic activity. TAK-593 selectively binds to and inhibits VEGFR and PDGFR, which may result in the inhibition of angiogenesis and tumor cell proliferation.;

UNII : H3I42X8XX7;

CAS number : 1005780-62-0;

Molecule name : TAK-593;

Details

Origin ID

C79794;

UMLS CUI

C2700135;

Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Receptor Tyrosine Kinase Inhibition [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Inhibition of Cell Proliferation [NCIt concept]
- Positive Regulation of Apoptosis [NCIt concept]
- Signal Transduction Inhibition [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Platelet-Derived Growth Factor Receptor [NCIt concept]
- Vascular Endothelial Growth Factor Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

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