" /> Pazopanib - CISMeF





Preferred Label : Pazopanib;

NCIt synonyms : Benzenesulfonamide, 5-((4-((2,3-dimethyl-2H-indazol-6-yl)methylamino)-2-pyrimidinyl)amino)-2-methyl-; Pazopanib Base;

NCIt related terms : GW786034;

NCIt definition : A small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial growth factor receptors (VEGFR)-1, -2 and -3, c-kit and platelet derived growth factor receptor (PDGF-R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated.;

Alternative definition : NCI-GLOSS: A drug that is used to treat kidney cancer and is being studied in the treatment of other types of cancer. It may prevent the growth of new blood vessels that tumors need to grow. It is a type of protein tyrosine kinase inhibitor and a type of antiangiogenesis agent.;

UNII : 7RN5DR86CK;

InChIKey : CUIHSIWYWATEQL-UHFFFAOYSA-N;

CAS number : 444731-52-6; 790713-33-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 444731-52-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 790713-33-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : GW786034;

Chemical formula : C21H23N7O2S;

Codes from synonyms : CDR0000321375; 387;

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14/05/2024


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