NCIt definition : The hydrochloride salt of a small molecule inhibitor of multiple protein tyrosine
kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular
endothelial growth factor receptors (VEGFR)-1, -2 and -3, c-kit and platelet derived
growth factor receptor (PDGF-R), which may result in inhibition of angiogenesis in
tumors in which these receptors are upregulated.;
Alternative definition : NCI-GLOSS: A drug that is used to treat kidney cancer and is being studied in the
treatment of other types of cancer. It may prevent the growth of new blood vessels
that tumors need to grow. It is a type of protein tyrosine kinase inhibitor and a
type of antiangiogenesis agent.;
UNII : 33Y9ANM545;
InChIKey : MQHIQUBXFFAOMK-UHFFFAOYSA-N;
CAS number : 635702-64-6;
Drug name : Votrient; Pazopater;
Molecule name : GW 786034B; GW-786034B;
Chemical formula : C21H23N7O2S.HCl;
NSC code : 737754;
Codes from synonyms : CDR0000527219; CDR0000658368;