" /> Motesanib Diphosphate - CISMeF





Preferred Label : Motesanib Diphosphate;

NCIt synonyms : 3-Pyridinecarboxamide, N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2-((4-pyridinylmethyl)amino)-, phosphate (1:2);

NCIt related terms : AMG 706;

NCIt definition : The orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplastic activity. Motesanib selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-derived growth factor (PDGFR), kit, and Ret receptors, thereby inhibiting angiogenesis and cellular proliferation.;

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of some types of cancer. It belongs to the families of drugs called angiogenesis inhibitors and protein kinase inhibitors.;

UNII : T6Q3060U91;

InChIKey : ONDPWWDPQDCQNJ-UHFFFAOYSA-N;

CAS number : 857876-30-3;

Molecule name : AMG 706; AMG-706;

Chemical formula : C22H23N5O.2H3O4P;

Codes from synonyms : CDR0000430871;

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01/06/2025


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