receptors, platelet-derived growth factor

Preferred Label : receptors, platelet-derived growth factor;

MeSH definition : Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA) and the beta PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types.;

MeSH synonym : pdgf receptor; pdgf receptors; platelet derived growth factor receptor; platelet derived growth factor receptors; platelet-derived growth factor receptor; platelet-derived growth factor receptors; receptor, pdgf; receptors, pdgf; receptors, platelet derived growth factor;

CISMeF synonym : EC 2.7.1.112;

Registry Number MeSH : EC 2.7.10.1;

MeSH annotation : DF: RECEPT PDGF;

Is substance : O;

UNII : EC 2.7.10.1;

Details

Origin ID

D017479;

UMLS CUI

C0071253;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- PDGFRB wt Allele [NCIt concept]
- Platelet-Derived Growth Factor Receptor-Like Protein [NCIt concept]
- Platelet-derived growth factor receptor [LOINC component]
- platelet-derived growth factor [SNOMED Notion]
Currated CISMeF NLP mapping
- Platelet-Derived Growth Factor Receptor [NCIt concept]
Indexing information
- (6,7-dimethoxy-2,4-dihydroindeno(1,2-c)pyrazol-3-yl)(3-fluorophenyl)amine [MeSH Supplementary Concept]
- 6,7-dimethoxy-3-phenylquinoxaline [MeSH Supplementary Concept]
- N-(4-((6,7-dimethoxy-4-quinolyl)oxy)phenyl)-N'-(2-methylbenzoyl)thiourea [MeSH Supplementary Concept]
- TAK 593 [MeSH Supplementary Concept]
- THRX 165724 [MeSH Supplementary Concept]
- ki 6896 [MeSH Supplementary Concept]
- pvr protein, drosophila [MeSH Supplementary Concept]
Record concept(s)
- receptors, Platelet-Derived growth factor [MeSH concept]
Related MeSH Supplementary Concept(s)
- 740Y-P [MeSH Supplementary Concept]
- PDGF receptor tyrosine kinase [MeSH Supplementary Concept]
- PDGFRL protein, human [MeSH Supplementary Concept]
See also
- platelet-derived growth factor [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- Platelet-Derived Growth Factor Receptor [NCIt concept]
- Platelet-derived growth factor receptor [LOINC component]

Keyword's position in hierarchy(ies) :

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