" /> PDGFRB wt Allele - CISMeF





Preferred Label : PDGFRB wt Allele;

NCIt synonyms : PDGF-R-Beta; Platelet-Derived Growth Factor Receptor, Beta Polypeptide wt Allele; PDGFR1; JTK12; PDGFR; PDGFRB; PDGFR Beta; CD140B;

NCIt definition : Human PDGFRB wild-type allele is located within 5q31-q32 and is approximately 42 kb in length. This allele, which encodes beta platelet-derived growth factor receptor protein, is involved in mitogenesis for cells of mesenchymal origin. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.;

NCIt note : This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome.;

GenBank Accession Number : NM_002609;

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10/07/2025


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