vascular endothelial growth factor a

Preferred Label : vascular endothelial growth factor a;

MeSH definition : The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as tumor angiogenesis factor and vascular permeability factor. Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.;

MeSH synonym : vasculotropin; vascular endothelial growth factor; vegf; vascular permeability factor; permeability factor, vascular; vegf-a; vascular endothelial growth Factor-A;

MeSH hyponym : Glioma-Derived vascular endothelial cell growth factor; Glioma Derived Vascular Endothelial Cell Growth Factor; GD-VEGF;

Is substance : O;

Details

Origin ID

D042461;

UMLS CUI

C0078058;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Recombinant Vascular Endothelial Growth Factor [NCIt concept]
- Vascular Endothelial Growth Factor A [NCIt concept]
- Vascular endothelial growth factor (substance) [SNOMED CT concept]
- Vascular endothelial growth factor a [OMIM gene]
False automatic mappings
- PSA Velocity [NCIt concept]
Indexing information
- FP3 VEGF receptor fc-fusion protein [MeSH Supplementary Concept]
- Flt(1-3)-IgG [MeSH Supplementary Concept]
- arginyl-arginyl-lysyl-arginyl-arginyl-arginine [MeSH Supplementary Concept]
- pegaptanib [MeSH Supplementary Concept]
Record concept(s)
- Glioma-Derived vascular endothelial cell growth factor [MeSH concept]
- vascular endothelial growth factor A [MeSH concept]
Related MeSH Supplementary Concept(s)
- 64Cu-DOTA-VEGF(DEE) [MeSH Supplementary Concept]
- VEGF-Ax protein, human [MeSH Supplementary Concept]
- VEGFA protein, human [MeSH Supplementary Concept]
- Vegfaa protein, zebrafish [MeSH Supplementary Concept]
- human vascular endothelial growth factor-staphylococcal enterotoxin A fusion protein [MeSH Supplementary Concept]
- technetium 99m HYNIC-vascular endothelial growth factor [MeSH Supplementary Concept]
- vammin protein, vipera ammodytes ammodytes [MeSH Supplementary Concept]
- vascular endothelial growth factor A (138-165) [MeSH Supplementary Concept]
- vascular endothelial growth factor A, mouse [MeSH Supplementary Concept]
- vascular endothelial growth factor A, rat [MeSH Supplementary Concept]
- vegfa.L protein, Xenopus [MeSH Supplementary Concept]
See also
- Ranibizumab [MeSH Descriptor]
- endothelial growth factors [MeSH Descriptor]
See also (suggested by CISMeF)
- abicipar pegol [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Vascular Endothelial Growth Factor A Measurement [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Vascular endothelial growth factor [LOINC component]
- Vascular endothelial growth factor (substance) [SNOMED CT concept]
- Vascular endothelial growth factor A [LOINC component]

Keyword's position in hierarchy(ies) :

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