epidermal growth factor

Preferred Label : epidermal growth factor;

MeSH definition : A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form.;

MeSH synonym : egf; epidermal growth factor-urogastrone; growth factor, epidermal; growth factor-urogastrone, epidermal; human urinary gastric inhibitor; urogastrone; beta urogastrone; beta-Urogastrone;

CISMeF synonym : growth factors, epidermal;

MeSH CAS label : epidermal growth factor;

Registry Number MeSH : 62229-50-9;

Wikipedia link : https://en.wikipedia.org/wiki/Epidermal growth factor;

Codes EINECS : 263-468-7;

Is substance : O;

Details

Origin ID

D004815;

UMLS CUI

C0242275;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- EGF Gene [NCIt concept]
- Epidermal Growth Factor Measurement [NCIt concept]
- Epidermal growth factor [OMIM gene]
- Nepidermin [NCIt concept]
- epidermal growth factor [ORDO Gene]
- epidermal growth factor [HGNC gene]
- epidermal growth factor receptor binding [GO term]
CISMeF manual mappings
- epidermal growth factor [Substance BNPC]
Indexing information
- ADGRE5 protein, human [MeSH Supplementary Concept]
- Adgre1 protein, rat [MeSH Supplementary Concept]
- Adgre4 protein, rat [MeSH Supplementary Concept]
- Adgre5 protein, mouse [MeSH Supplementary Concept]
- Adgre5 protein, rat [MeSH Supplementary Concept]
- CRELD1 protein, human [MeSH Supplementary Concept]
- CRELD1 protein, mouse [MeSH Supplementary Concept]
- CRELD2 protein, human [MeSH Supplementary Concept]
- CRELD2 protein, mouse [MeSH Supplementary Concept]
- EGFR protein, human [MeSH Supplementary Concept]
- Impg2 protein, rat [MeSH Supplementary Concept]
- LRP protein, holotrichia diomphalia [MeSH Supplementary Concept]
- SCUBE3 protein, human [MeSH Supplementary Concept]
- Scube2 protein, mouse [MeSH Supplementary Concept]
- Scube3 protein, mouse [MeSH Supplementary Concept]
- UBQLN1 protein, human [MeSH Supplementary Concept]
- exogastrula-inducing peptide A, anthocidaris crassispina [MeSH Supplementary Concept]
- exogastrula-inducing peptide C, anthocidaris crassispina [MeSH Supplementary Concept]
- exogastrula-inducing peptide D, anthocidaris crassispina [MeSH Supplementary Concept]
- fibrillin protein, podocoryne carnea [MeSH Supplementary Concept]
- polydom protein, mouse [MeSH Supplementary Concept]
- tdgf1 protein, zebrafish [MeSH Supplementary Concept]
Record concept(s)
- epidermal growth factor [MeSH concept]
Related MeSH Supplementary Concept(s)
- 111In-DTPA-human epidermal growth factor [MeSH Supplementary Concept]
- 68Ga-DOTA-hEGF [MeSH Supplementary Concept]
- CALEB protein, chicken [MeSH Supplementary Concept]
- CEGP-003 [MeSH Supplementary Concept]
- E 6010 [MeSH Supplementary Concept]
- E1-INT [MeSH Supplementary Concept]
- EGF-genistein [MeSH Supplementary Concept]
- Emr4 protein, mouse [MeSH Supplementary Concept]
- FAT3 protein, human [MeSH Supplementary Concept]
- Fat3 protein, rat [MeSH Supplementary Concept]
- Fcy-hEGF fusion protein [MeSH Supplementary Concept]
- HmEGFL-1 protein, herdmania momus [MeSH Supplementary Concept]
- Lin-3 protein, C elegans [MeSH Supplementary Concept]
- Ly64 protein, mouse [MeSH Supplementary Concept]
- Tdgf1 protein, mouse [MeSH Supplementary Concept]
- biotinyl epidermal growth factor [MeSH Supplementary Concept]
- biregulin [MeSH Supplementary Concept]
- epidermal growth factor (1-45) [MeSH Supplementary Concept]
- epidermal growth factor (1-48) [MeSH Supplementary Concept]
- epidermal growth factor (1-53) [MeSH Supplementary Concept]
- epidermal growth factor (32-48), Cys-SO3H(33,42)- [MeSH Supplementary Concept]
- epidermal growth factor (33-42) [MeSH Supplementary Concept]
- epidermal growth factor precursor [MeSH Supplementary Concept]
- epidermal growth factor, Lys(3)-Tyr(22)- [MeSH Supplementary Concept]
- epidermal growth factor--dextran-tyrosine conjugate [MeSH Supplementary Concept]
- epidermal growth factor-dextran conjugate [MeSH Supplementary Concept]
- epidermal growth factor-like protein, S(1-5) [MeSH Supplementary Concept]
- epidermal growth factor-ricin complex [MeSH Supplementary Concept]
- epidermal growth inhibitors [MeSH Supplementary Concept]
- fat-3 protein, C elegans [MeSH Supplementary Concept]
- fibropellin protein, sea urchin [MeSH Supplementary Concept]
- gigantoxin I, stichodactyla gigantea [MeSH Supplementary Concept]
- growth factors, combined defect of [MeSH Supplementary Concept]
- humatrix [MeSH Supplementary Concept]
- peptabody-EGF [MeSH Supplementary Concept]
- pseudomonas exotoxin-epidermal growth factor conjugate [MeSH Supplementary Concept]
- spi protein, drosophila [MeSH Supplementary Concept]
- technetium 99m HYNIC-human epidermal growth factor [MeSH Supplementary Concept]
- technetium tc 99m epidermal growth factor [MeSH Supplementary Concept]
- urogastrone, lys-beta- [MeSH Supplementary Concept]
See also
- ErbB Receptors [MeSH Descriptor]
- anti-ulcer agents [MeSH Descriptor]
- gastrointestinal agents [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Epidermal Growth Factor [NCIt concept]
- Epidermal growth factor [LOINC component]
- Epidermal growth factor (substance) [SNOMED CT concept]
- epidermal growth factor [Substance BNPC]
- epidermal growth factor [SNOMED Notion]

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