receptors, vascular endothelial growth factor

Preferred Label : receptors, vascular endothelial growth factor;

MeSH definition : A family of closely related RECEPTOR PROTEIN-TYROSINE KINASES that bind vascular endothelial growth factors. They share a cluster of seven extracellular Ig-like domains which are important for ligand binding. They are highly expressed in vascular endothelial cells and are critical for the physiological and pathological growth, development and maintenance of blood and lymphatic vessels.;

MeSH synonym : receptor, vascular endothelial cell growth factor; receptor, vascular permeability factor; receptors, vegf; vascular endothelial cell growth factor receptor; vascular endothelial growth factor receptor; vascular permeability factor receptor; vegf receptor; vegf receptors; vpf receptor;

CISMeF synonym : EC 2.7.1.112;

MeSH Hyperonym : endothelial growth factor receptor; Receptor, Endothelial Growth Factors;

Registry Number MeSH : EC 2.7.10.1;

MeSH annotation : GEN; prefer specifics, DF: VEGF RECEPT; general; prefer specifics;

Wikipedia link : https://en.wikipedia.org/wiki/Receptors, vascular endothelial growth factor;

Is substance : O;

UNII : EC 2.7.10.1;

Details

Origin ID

D040262;

UMLS CUI

C0148199;

ATC code(s)
- Vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Currated CISMeF NLP mapping
- Vascular Endothelial Growth Factor Receptor [NCIt concept]
- Vascular Endothelial Growth Factor Receptor 1 [NCIt concept]
Indexing information
- (4-(4'-chloro-2'-fluoro)phenylamino)-6,7-dimethylquinazoline [MeSH Supplementary Concept]
- 3-(5-methyl-2-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl)propionic acid [MeSH Supplementary Concept]
- 4-(2-(5-cyanothiazol-2-ylamino)pyridin-4-ylmethyl)piperazine-1-carboxylic acid methylamide [MeSH Supplementary Concept]
- AEE 788 [MeSH Supplementary Concept]
- BSF 476921 [MeSH Supplementary Concept]
- GSK 1363089 [MeSH Supplementary Concept]
- GW 654652 [MeSH Supplementary Concept]
- N-(2-chloro-4-((6,7-dimethoxy-4-quinolyl)oxy)phenyl)-N'-(5-methyl-3-isoxazolyl)urea [MeSH Supplementary Concept]
- PF 00337210 [MeSH Supplementary Concept]
- Sorafenib [MeSH Descriptor]
- TAK 593 [MeSH Supplementary Concept]
- farnesiferol C [MeSH Supplementary Concept]
- pazopanib [MeSH Supplementary Concept]
- pvr protein, drosophila [MeSH Supplementary Concept]
- tivozanib [MeSH Supplementary Concept]
Record concept(s)
- endothelial growth factor receptor [MeSH concept]
- receptors, vascular endothelial growth factor [MeSH concept]
Related MeSH Supplementary Concept(s)
- VEGF-Trap fusion protein, recombinant [MeSH Supplementary Concept]
- aflibercept [MeSH Supplementary Concept]
- dear protein, rat [MeSH Supplementary Concept]
See also
- Bevacizumab [MeSH Descriptor]
- Immunoglobulin Domains [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- Vascular Endothelial Growth Factor Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

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