Recombinant Vascular Endothelial Growth Factor

Preferred Label : Recombinant Vascular Endothelial Growth Factor;

NCIt synonyms : Vascular Permeability Factor; VPF; VEGF; rhuVEGF; Therapeutic Vascular Endothelial Growth Factor;

NCIt related terms : vascular endothelial growth factor;

NCIt definition : A recombinant therapeutic agent which is chemically identical to or similar to endogenous vascular endothelial growth factor (VEGF). Produced by a wide variety of cell types, endogenous VEGF is a homodimeric, glycosylated protein that is a highly specific mitogen for vascular endothelial cells; significantly influences vascular permeability; appears to play a role in neovascularisation under physiological conditions; is a potent chemoattractant; has pro-coagulatory activities; and is hypoxia-inducible. Therapeutic VEGF may be used to induce angiogenesis in the treatment of ischemic conditions and may have a role in stimulating nerve regeneration. (NCI04);

Codes from synonyms : CDR0000044222;

Details

Origin ID

C1272;

UMLS CUI

C1522575;

Automatic exact mappings (from CISMeF team)
- Vascular endothelial growth factor A [LOINC component]
- vascular endothelial growth factor A [HGNC gene]
- vascular endothelial growth factor b [MeSH Descriptor]
- vascular endothelial growth factor c [MeSH Descriptor]
- vascular endothelial growth factor d [MeSH Descriptor]
- vascular endothelial growth factor receptor binding [GO term]
Currated CISMeF NLP mapping
- Vascular endothelial growth factor (substance) [SNOMED CT concept]
- Vascular endothelial growth factor a [OMIM gene]
- vascular endothelial growth factor A [MeSH concept]
- vascular endothelial growth factor a [MeSH Descriptor]
- vascular endothelial growth factors [MeSH Descriptor]
- vascular endothelial growth factors [MeSH concept]
False automatic mappings
- Vascular endothelial growth factor [LOINC component]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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