Preferred Label : pegaptanib;
MeSH note : a 28-base ribonucleic acid aptamer covalently linked to two branched 20-kD polyethylene
glycol moieties to block the activity of extracellular VEGF, specifically the 165-amino-acid
isoform (VEGF165); for treatment of neovascular age-related macular degeneration;
CISMeF synonym : macugen;
Is substance : O;
UNII : 2H1PA8H1EN;
Origin ID : C495058;
UMLS CUI : C1531015;
ATC code(s)
ATC code(s)
Currated CISMeF NLP mapping
MeSH indexing information
MeSH term(s) associated for indexing
Record concept(s)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
http://www.has-sante.fr/portail/jcms/c_1714255/fr/macugen
http://www.has-sante.fr/portail/jcms/c_1714254/fr/macugen04122013avisct12846
http://www.has-sante.fr/portail/display.jsp?id=c_468470
2013
false
France
French
evaluation of the transparency committee
pegaptanib
pegaptanib
intravitreal injections
wet macular degeneration
insurance, health, reimbursement
vascular endothelial growth factor a
treatment outcome
aptamers, nucleotide
guidelines for drug use
---
https://www.ema.europa.eu/medicines/human/EPAR/Macugen
2012
United Kingdom
French
English
syndication feed
adult
aged
aged, 80 and over
aptamers, nucleotide
aptamers, nucleotide
treatment outcome
drug evaluation
drug approval
drug labeling
vascular endothelial growth factor a
choroidal neovascularization
pregnancy
drug evaluation, preclinical
drug compounding
pegaptanib
pegaptanib
pegaptanib
wet macular degeneration
intravitreal injections
drug evaluation
package leaflet
summary of product characteristics
---
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailOne.php?lang=fr&linkID=SBD00091
2011
false
false
false
Canada
drug information
injections
pegaptanib
sodium
pegaptanib
---
https://www.cadth.ca/sites/default/files/pdf/460_Neovascular-Age-Related-Macular-Degeneration_to_f.pdf
https://www.cadth.ca/fr/traitement-de-la-degenerescence-maculaire-liee-lage-neovasculaire-analyse-systematique-des-classes
2008
true
Canada
French
Ranibizumab
macular degeneration
pegaptanib
pegaptanib
aptamers, nucleotide
drug evaluation
economic evaluation
---
http://www.meddispar.fr/medicaments/3826083
2008
France
French
aptamers, nucleotide
drug prescriptions
macular degeneration
legislation, drug
pegaptanib
pegaptanib
drug information
---
https://www.cadth.ca/sites/default/files/cdr/complete/cdr_complete_Macugen-Fr.pdf
2006
Canada
French
choroidal neovascularization
aptamers, nucleotide
pegaptanib
pegaptanib
intravitreal injections
vascular endothelial growth factor a
macular degeneration
drug evaluation
---
https://www.cadth.ca/sites/default/files/pdf/367_pegaptanib_cetap_f.pdf
https://www.cadth.ca/sites/default/files/pdf/367_pegaptanib_cetap_e.pdf
2005
Canada
French
English
macular degeneration
canada
vascular endothelial growth factor a
aptamers, nucleotide
aptamers, nucleotide
treatment outcome
choroidal neovascularization
drug costs
clinical trials as topic
visual acuity
Evidence-Based medicine
injections
vitreous body
pegaptanib
pegaptanib
pegaptanib
pegaptanib
aptamers, nucleotide
aptamers, nucleotide
drug evaluation
---