Preferred Label : pegaptanib;
MeSH note : a 28-base ribonucleic acid aptamer covalently linked to two branched 20-kD polyethylene
glycol moieties to block the activity of extracellular VEGF, specifically the 165-amino-acid
isoform (VEGF165); for treatment of neovascular age-related macular degeneration;
CISMeF synonym : macugen;
Is substance : O;
UNII : 2H1PA8H1EN;
Origin ID : C495058;
UMLS CUI : C1531015;
ATC code(s)
ATC code(s)
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
MeSH indexing information
MeSH term(s) associated for indexing
Record concept(s)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
http://www.has-sante.fr/jcms/c_1714255/fr/macugen
http://www.has-sante.fr/jcms/c_1714254/fr/macugen04122013avisct12846
http://www.has-sante.fr/display.jsp?id=c_468470
2013
false
France
French
evaluation of the transparency committee
pegaptanib
pegaptanib
intravitreal injections
wet macular degeneration
insurance, health, reimbursement
vascular endothelial growth factor a
treatment outcome
aptamers, nucleotide
guidelines for drug use
---
https://www.ema.europa.eu/medicines/human/EPAR/Macugen
2012
United Kingdom
French
English
syndication feed
adult
aged
aged, 80 and over
aptamers, nucleotide
aptamers, nucleotide
treatment outcome
drug evaluation
drug approval
drug labeling
vascular endothelial growth factor a
choroidal neovascularization
pregnancy
drug evaluation, preclinical
drug compounding
pegaptanib
pegaptanib
pegaptanib
wet macular degeneration
intravitreal injections
drug evaluation
package leaflet
summary of product characteristics
---
https://hpr-rps.hres.ca/reg-content/sommaire-motif-decision-detailOne.php?lang=fr&linkID=SBD00091
2011
false
false
false
Canada
drug information
injections
pegaptanib
sodium
pegaptanib
---
https://www.cadth.ca/sites/default/files/pdf/460_Neovascular-Age-Related-Macular-Degeneration_to_f.pdf
https://www.cadth.ca/fr/traitement-de-la-degenerescence-maculaire-liee-lage-neovasculaire-analyse-systematique-des-classes
2008
true
Canada
French
Ranibizumab
macular degeneration
pegaptanib
pegaptanib
aptamers, nucleotide
drug evaluation
economic evaluation
---
http://www.meddispar.fr/medicaments/3826083
2008
France
French
aptamers, nucleotide
drug prescriptions
macular degeneration
legislation, drug
pegaptanib
pegaptanib
drug information
---
https://www.cadth.ca/sites/default/files/cdr/complete/cdr_complete_Macugen-Fr.pdf
2006
Canada
French
choroidal neovascularization
aptamers, nucleotide
pegaptanib
pegaptanib
intravitreal injections
vascular endothelial growth factor a
macular degeneration
drug evaluation
---
https://www.cadth.ca/sites/default/files/pdf/367_pegaptanib_cetap_f.pdf
https://www.cadth.ca/sites/default/files/pdf/367_pegaptanib_cetap_e.pdf
2005
Canada
French
English
macular degeneration
canada
vascular endothelial growth factor a
aptamers, nucleotide
aptamers, nucleotide
treatment outcome
choroidal neovascularization
drug costs
clinical trials as topic
visual acuity
Evidence-Based medicine
injections
vitreous body
pegaptanib
pegaptanib
pegaptanib
pegaptanib
aptamers, nucleotide
aptamers, nucleotide
drug evaluation
---