ADAM17 wt Allele

Preferred Label : ADAM17 wt Allele;

NCIt synonyms : NISBD; ADAM18; Tumor Necrosis Factor, Alpha, Converting Enzyme Gene; TACE; A Disintegrin and Metalloproteinase Domain 17 Gene; CD156B; NISBD1; ADAM Metallopeptidase Domain 17 wt Allele; cSVP; A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, Alpha, Converting Enzyme) Gene;

NCIt definition : Human ADAM17 wild-type allele is located within 2p25 and is approximately 66 kb in length. This allele, which encodes ADAM17 protein, is involved in the cleavage of membrane-bound cell-surface proteins to release their mature soluble forms.;

GenBank Accession Number : NM_003183;

Details

Origin ID

C49722;

UMLS CUI

C1706637;

OMIM relation
- A disintegrin and metalloproteinase domain 17 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 2p25 [NCIt concept]
gene_is_element_in_pathway
- Alzheimer's Disease Pathway KEGG [NCIt concept]
- ERBB4 Signaling Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
- Gamma-Secretase Mediated ErbB4 Signaling Pathway [NCIt concept]
- Nerve Growth Factor Receptor Signaling Pathway [NCIt concept]
- Notch Signaling Pathway [NCIt concept]
- Notch and Wnt Signaling Pathway [NCIt concept]
- Segmentation Clock Pathway [NCIt concept]
- TNF Receptor Family Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Hydrolysis [NCIt concept]
- Integrin Binding [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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