IKBKB wt Allele

Preferred Label : IKBKB wt Allele;

NCIt synonyms : Nuclear Factor of Kappa Light Chain Gene Enhancer in B Cells, Kinase of, Beta Gene; MGC131801; IKKB; FLJ38368; FLJ33771; FLJ40509; FLJ36218; IKK-beta; NFKBIKB; IKK2; Inhibitor of Kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase Beta Gene; Inhibitor of Nuclear Factor Kappa B Kinase Subunit Beta wt Allele; IMD15A; IMD15; IMD15B; Inhibitor of Kappa Light Polypeptide Gene Enhancer in B Cells, Kinase of, Beta Gene;

NCIt definition : Human IKBKB wild-type allele is located in the vicinity of 8p11.21 and is approximately 61 kb in length. This allele, which encodes inhibitor of nuclear factor kappa-B kinase subunit beta protein, plays a role in the modulation of protein phosphorylation, apoptosis and signaling.;

NCIt note : Mutations in the protein-coding region of the IKBKB gene were found in multiple myeloma. (Nature. 2011; 471: 467-472.);

GenBank Accession Number : AF029684;

Details

Origin ID

C96384;

UMLS CUI

C3272750;

OMIM relation
- Inhibitor of nuclear factor kappa-b kinase, subunit beta [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 8p11.21 [NCIt concept]
gene_is_element_in_pathway
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Adipocytokine Signaling Pathway [NCIt concept]
- Apoptosis Pathway [NCIt concept]
- Atypical NF-kappaB Signaling Pathway [NCIt concept]
- B Cell Receptor Signaling Pathway [NCIt concept]
- BCR Immune Response Signaling Pathway [NCIt concept]
- Canonical NF-kappaB Signaling Pathway [NCIt concept]
- Chagas Disease Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- Cytosolic DNA-Sensing Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
- FAS Signaling Pathway PID [NCIt concept]
- FOXO Transcription Factor Family Signaling Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- IL1-Mediated Signaling Pathway [NCIt concept]
- IL1R Signaling Pathway [NCIt concept]
- Insulin Signaling Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- NFKB Signaling Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- Nerve Growth Factor Receptor Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Pancreatic Cancer Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
- Shigellosis Pathway [NCIt concept]
- Small Cell Lung Cancer Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- TNF Receptor Family Signaling Pathway [NCIt concept]
- TNF Stress Related Signaling Pathway [NCIt concept]
- TRAIL Signaling Pathway [NCIt concept]
- Toll-Like Receptor Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
- Type II Diabetes Mellitus Pathway [NCIt concept]
- mTOR Signaling Pathway PID [NCIt concept]
gene_plays_role_in_process
- Negative Regulation of Apoptosis [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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