Proto-Oncogene Tyrosine-Protein Kinase Src

Preferred Label : Proto-Oncogene Tyrosine-Protein Kinase Src;

NCIt synonyms : p60src; SRC; Proto-Oncogene c-Src; pp60c-src; p60-SRC; EC 2.7.10.2;

NCIt definition : Proto-oncogene tyrosine-protein kinase Src (536 aa, 60 kDa) is encoded by the human SRC gene. This protein is involved in both receptor-mediated signal transduction and tyrosine phosphorylation.;

Details

Origin ID

C17389;

UMLS CUI

C3853644;

OMIM relation
- Src protooncogene, nonreceptor tyrosine kinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- SRC Family Gene [NCIt concept]
- SRC Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- SH2 Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Tyrosine Kinase Domain [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Adherens Junction Assembly Pathway [NCIt concept]
- Adherens Junction Formation Pathway [NCIt concept]
- Agrin Pathway [NCIt concept]
- Androgen Receptor Regulation Pathway [NCIt concept]
- Angiotensin II Signaling Pathway [NCIt concept]
- Arf6 Signaling Pathway [NCIt concept]
- Aspirin Inhibition of Platelet Activation Pathway [NCIt concept]
- Atypical NF-kappaB Signaling Pathway [NCIt concept]
- Bacterial Invasion of Epithelial Cell Pathway [NCIt concept]
- CXCR3-Mediated Signaling Pathway [NCIt concept]
- Calpain-1 Cell Spread Pathway [NCIt concept]
- Cell to Cell Adhesion Signaling Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- E-Cadherin Signaling Pathway in Keratinocytes [NCIt concept]
- EGF Receptor Downregulation by CBL Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- ERBB2/ERBB3 Signaling Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- Endothelin Pathway [NCIt concept]
- Ephrin A2 Forward Signaling Pathway [NCIt concept]
- Ephrin B Forward Signaling Pathway [NCIt concept]
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
- Erk1/Erk2 MAPK Signaling Pathway [NCIt concept]
- Extracellular Matrix Binding Pathway [NCIt concept]
- FAS Signaling Pathway PID [NCIt concept]
- FGF Signaling Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- GABA Receptor Life Cycle Pathway [NCIt concept]
- GPCR Signaling Pathway [NCIt concept]
- Gap Junction Assembly Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- HBx Signaling Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway BioCarta [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- Integrin Signaling Pathway [NCIt concept]
- Internalization Pathway for Epidermal Growth Factor Receptor [NCIt concept]
- Lysophosphatidic Acid Receptor Signaling Pathway [NCIt concept]
- NTRK1/PI3K/PLC-Gamma Signaling Pathway [NCIt concept]
- Nectin Adhesion Pathway [NCIt concept]
- Nongenotropic Androgen Signaling Pathway [NCIt concept]
- Oocyte Maturation Pathway [NCIt concept]
- PI3K/AKT1 Signaling Pathway [NCIt concept]
- PTP4A Family Signaling Pathway [NCIt concept]
- PTPN1 Signaling Pathway [NCIt concept]
- Pelp1 Estrogen Receptor Pathway [NCIt concept]
- Phospholipid Signaling Pathway [NCIt concept]
- Plasma Membrane Estrogen Receptor Signaling Pathway [NCIt concept]
- Proto-Oncogene Tyrosine-Protein Kinase Receptor Ret Signaling Pathway [NCIt concept]
- Pyk2 and Map Kinase Pathway [NCIt concept]
- Regulation of Apoptosis Pathway [NCIt concept]
- Rho Cell Motility Signaling Pathway [NCIt concept]
- SRC Tyrosine Kinase Activation Pathway [NCIt concept]
- Shigellosis Pathway [NCIt concept]
- Sphingosine 1-Phosphate Receptor 3 Signaling Pathway [NCIt concept]
- Splicing Regulation Pathway [NCIt concept]
- Sprouty Regulation of Tyrosine Kinase Signaling Pathway [NCIt concept]
- Syndecan-2-Mediated Signaling Pathway [NCIt concept]
- Syndecan-3-Mediated Signaling Pathway [NCIt concept]
- Tight Junction Assembly Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]
is_target
- Elzovantinib [NCIt concept]
- Enbezotinib [NCIt concept]
- Repotrectinib [NCIt concept]
- Rivoceranib [NCIt concept]
- Rivoceranib Mesylate [NCIt concept]
- SRC/YES1 Kinase Inhibitor NXP900 [NCIt concept]
- Saracatinib [NCIt concept]
- Src Kinase Inhibitor AP 23846 [NCIt concept]
- Src Kinase Inhibitor M475271 [NCIt concept]
- Src/tubulin Inhibitor KX2-361 [NCIt concept]
- Tirbanibulin [NCIt concept]
- Tyrosine Kinase Inhibitor XL228 [NCIt concept]

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