Rivoceranib Mesylate

Preferred Label : Rivoceranib Mesylate;

NCIt synonyms : Apatinib Mesylate;

NCIt definition : The mesylate salt of rivoceranib, an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. Rivoceranib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.;

UNII : TK02X14ASJ;

InChIKey : FYJROXRIVQPKRY-UHFFFAOYSA-N;

CAS number : 1218779-75-9;

Drug name : Aitan;

Molecule name : YN-968D1; YN 968D1;

Details

Origin ID

C74012;

UMLS CUI

C5553037;

Automatic exact mappings (from CISMeF team)
- apatinib mesylate [MeSH concept]
- rivoceranib mesylate [MeSH concept]
Currated CISMeF NLP mapping
- apatinib [MeSH concept]
- apatinib [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- apatinib [MeSH Supplementary Concept]
- apatinib [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_free_acid_or_base_form
- Rivoceranib [NCIt concept]
has_target
- Proto-Oncogene Tyrosine-Protein Kinase Src [NCIt concept]
- Tyrosine-Protein Kinase CSK [NCIt concept]
- Vascular Endothelial Growth Factor Receptor 2 [NCIt concept]
is_salt_form_of
- Rivoceranib [NCIt concept]

Keyword's position in hierarchy(ies) :

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