Rivoceranib - CISMeF

Preferred Label : Rivoceranib;

NCIt synonyms : -Pyridinecarboxamide, N-(4-(1-cyanocyclopentyl)phenyl)-2-((4-pyridinylmethyl)amino)-; Apatinib Free Base;

NCIt related terms : Apatinib;

NCIt definition : An orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. Upon administration, rivoceranib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.;

UNII : 5S371K6132;

InChIKey : WPEWQEMJFLWMLV-UHFFFAOYSA-N;

CAS number : 811803-05-1;

Molecule name : YN968D1 Free Base;

NCI Metathesaurus CUI : CL553441;

Codes from synonyms : 40;

Details

Origin ID

C152237;

UMLS CUI

C2346836;

Automatic exact mappings (from CISMeF team)
- rivoceranib [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- apatinib [MeSH Supplementary Concept]
- apatinib [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
has_salt_form
- Rivoceranib Mesylate [NCIt concept]
has_target
- Mast/Stem Cell Growth Factor Receptor Kit [NCIt concept]
- Proto-Oncogene Tyrosine-Protein Kinase Src [NCIt concept]
- Vascular Endothelial Growth Factor Receptor 2 [NCIt concept]
is_free_acid_or_base_form_of
- Rivoceranib Mesylate [NCIt concept]

Keyword's position in hierarchy(ies) :

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