" /> Src Kinase Inhibitor AP 23846 - CISMeF





Preferred Label : Src Kinase Inhibitor AP 23846;

NCIt definition : A novel small molecule Src family kinase inhibitor with potential antiangiogenic activity. Upon administration, Src kinase inhibitor AP23846 selectively binds to and stabilizes an inactive ATP-binding site conformation leading to reduced Src kinase activity. This may reduce the production of pro-angiogenic factors, vascular endothelial growth factor (VEGF) and interleukin (IL)-8. Src tyrosine kinases are upregulated in many tumor cells and play important roles in tumor cell proliferation, survival, migration, invasion and angiogenesis.;

CAS number : 878654-51-4;

Molecule name : AP-23846; AP 23846;

NCI Metathesaurus CUI : CL971115;

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07/05/2025


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