MAPK9 wt Allele

Preferred Label : MAPK9 wt Allele;

NCIt synonyms : JNK2Beta; JNK2B; JNK-55; p54aSAPK; JNK2; JNK2Alpha; PRKM9; JNK2A; Mitogen-Activated Protein Kinase 9 wt Allele;

NCIt definition : Human MAPK9 wild-type allele is located within 5q35 and is approximately 45 kb in length. This allele, which encodes mitogen-activated protein kinase 9 protein, is involved in the activation of nuclear transcription factors in response to environmental stress and pro-inflammatory cytokines, stabilization of the p53 tumor suppressor protein and differentiation of T-helper cells.;

NCIt note : The MAPK9 gene is involved in UV radiation-induced apoptosis. This gene encodes four isoforms (alpha-1, -2, and beta-1, -2) of mitogen-activated protein kinase 9 protein.;

GenBank Accession Number : NM_002752;

Détails

Origin ID

C51260;

UMLS CUI

C1708805;

OMIM relation
- Mitogen-activated protein kinase 9 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 5q35 [NCIt concept]
gene_is_element_in_pathway
- Adipocytokine Signaling Pathway [NCIt concept]
- Chagas Disease Pathway [NCIt concept]
- Colorectal Cancer Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Pancreatic Cancer Pathway [NCIt concept]
- Progesterone-Mediated Oocyte Maturation Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
- Salmonella Pathway [NCIt concept]
- Shigellosis Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
- Type II Diabetes Mellitus Pathway [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Stress Response Signaling [NCIt concept]
- T-Cell Proliferation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

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