NCIt definition : Human MAPK9 wild-type allele is located within 5q35 and is approximately 45 kb in
length. This allele, which encodes mitogen-activated protein kinase 9 protein, is
involved in the activation of nuclear transcription factors in response to environmental
stress and pro-inflammatory cytokines, stabilization of the p53 tumor suppressor protein
and differentiation of T-helper cells.;
NCIt note : The MAPK9 gene is involved in UV radiation-induced apoptosis. This gene encodes four
isoforms (alpha-1, -2, and beta-1, -2) of mitogen-activated protein kinase 9 protein.;