" /> PAK1 wt Allele - CISMeF





Preferred Label : PAK1 wt Allele;

NCIt synonyms : PAK1alpha; p21/Cdc42/Rac1-Activated Kinase 1 (STE20 Homolog, Yeast) wt Allele; p21-Activated Kinase 1 Gene;

NCIt definition : Human PAK1 wild-type allele is located within 11q13-q14 and is approximately 152 kb in length. This allele, which encodes serine/threonine-protein kinase PAK 1 protein, plays a role in the dissolution of stress fibers and reorganization of focal complexes.;

NCIt note : The PAK1 gene produces two RNA transcript variants via alternative splicing which encode two isoforms of the serine/threonine-protein kinase PAK 1 protein. Activity of this protein is inhibited in cells undergoing apoptosis.;

GenBank Accession Number : NM_002576;

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20/05/2024


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