p21-Activated kinases

Preferred Label : p21-Activated kinases;

MeSH definition : A family of serine-threonine kinases that bind to and are activated by MONOMERIC GTP-BINDING PROTEINS such as RAC GTP-BINDING PROTEINS and CDC42 GTP-BINDING PROTEIN. They are intracellular signaling kinases that play a role the regulation of cytoskeletal organization.;

MeSH synonym : kinases, p21-activated; pak kinases; kinases, pak; p21 activated kinases; PAK Kinase; Kinase, PAK; p21-Activated Kinase; Kinase, p21-Activated; p21 Activated Kinase;

MeSH hyponym : p21-Activated kinase 1; p21-Activated kinase 3; p21-Activated kinase 2; p21 Activated Kinase 2; p65(PAK); p65PAK Protein; PAK-2 Kinase; PAK 2 Kinase; PAK2 Kinase; PAK65; gamma-PAK; gamma PAK; p21 Activated Kinase 1; Serine-Threonine-Protein Kinase PAK 1; Serine Threonine Protein Kinase PAK 1; alpha p21-Activated Kinase; alpha p21 Activated Kinase; alpha-PAK; PAK1 Kinase; PAK-1 Kinase; PAK 1 Kinase; p21 Activated Kinase 3; Oligophrenin-3; Oligophrenin 3; Serine-Threonine-Protein Kinase PAK 3; Serine Threonine Protein Kinase PAK 3; PAK3 Kinase; beta p21-Activated Kinase; beta p21 Activated Kinase; p21-Activated Kinase, beta; beta-PAK;

MeSH Related Number : p21-Activated kinase 1; p21-Activated kinase 2; p21-Activated kinase 3; EC 2.7.11.1;

Registry Number MeSH : EC 2.7.11.1;

Related CAS MeSH : EC 2.7.11.1 (p21-Activated kinase 3); EC 2.7.11.1 (p21-Activated kinase 1); EC 2.7.11.1 (p21-Activated kinase 2);

Wikipedia link : https://en.wikipedia.org/wiki/P21-activated kinases;

Is substance : O;

UNII : EC 2.7.11.1;

Details

Origin ID

D054462;

UMLS CUI

C1955933;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- 6-(2,4-dichlorophenyl)-8-ethyl-2-(3-fluoro-4-(piperazin-1-yl)phenylamino)pyrido(2,3-d)pyrimidin-7(8H)-one [MeSH Supplementary Concept]
- FRAX597 [MeSH Supplementary Concept]
- PF 3758309 [MeSH Supplementary Concept]
Record concept(s)
- p21-Activated kinase 1 [MeSH concept]
- p21-Activated kinase 2 [MeSH concept]
- p21-Activated kinase 3 [MeSH concept]
- p21-Activated kinases [MeSH concept]
Related MeSH Supplementary Concept(s)
- PAK protein, entamoeba histolytica [MeSH Supplementary Concept]
- PAK1 protein, human [MeSH Supplementary Concept]
- PAK2 protein, human [MeSH Supplementary Concept]
- PAK3 protein, human [MeSH Supplementary Concept]
- PAK4 protein, human [MeSH Supplementary Concept]
- PAK4 protein, xenopus [MeSH Supplementary Concept]
- PAK4 protein, zebrafish [MeSH Supplementary Concept]
- PAK5 protein, human [MeSH Supplementary Concept]
- PAK6 protein, human [MeSH Supplementary Concept]
- Pak1 protein, mouse [MeSH Supplementary Concept]
- Pak1 protein, rat [MeSH Supplementary Concept]
- Pak2 protein, mouse [MeSH Supplementary Concept]
- Pak2 protein, rat [MeSH Supplementary Concept]
- Pak3 protein, mouse [MeSH Supplementary Concept]
- Pak3 protein, rat [MeSH Supplementary Concept]
- Pak4 protein, mouse [MeSH Supplementary Concept]
- Pak4 protein, rat [MeSH Supplementary Concept]
- Pak6 protein, mouse [MeSH Supplementary Concept]
- Pak7 protein, mouse [MeSH Supplementary Concept]
- X-PAK5 protein, xenopus [MeSH Supplementary Concept]
- pak protein, drosophila [MeSH Supplementary Concept]
- pak-1 protein, C elegans [MeSH Supplementary Concept]
- shk1 protein, S pombe [MeSH Supplementary Concept]
- shk2 protein, S pombe [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients