NCIt definition : Human CSK wild-type allele is located within 15q23-q25 and is approximately 21 kb
in length. This allele, which encodes tyrosine-protein kinase CSK protein, plays a
role in signal transduction and intercellular signaling.;
NCIt note : The primary substrate for tyrosine-protein kinase CSK protein is proto-oncogene tyrosine-protein
kinase LCK, which is negatively regulated via phosphorylation of Tyr-504.;