MET wt Allele - CISMeF

Preferred Label : MET wt Allele;

NCIt synonyms : RCCP2; MET; HGFR Gene; AUTS9; Hepatocyte Growth Factor Receptor Gene; MET Proto-Oncogene, Receptor Tyrosine Kinase wt Allele; Met Proto-Oncogene (Hepatocyte Growth Factor Receptor) Gene; c-Met; DFNB97; C-MET wt Allele;

NCIt definition : Human MET wild-type allele is located within 7q31 and is approximately 126 kb in length. This allele, which encodes hepatocyte growth factor receptor protein, plays a role in the regulation of cellular tyrosine-kinase activity. Mutations in the MET gene are associated with papillary renal carcinoma.;

GenBank Accession Number : J02958;

Details

Origin ID

C51540;

UMLS CUI

C1704823;

OMIM relation
- Met protooncogene, receptor tyrosine kinase [OMIM gene]
See also inter- (CISMeF)
- Deafness, autosomal recessive 97 [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_abnormality
- MET Gene Mutation [NCIt concept]
gene_has_physical_location
- 7: 115906410-116032391 [NCIt concept]
gene_in_chromosomal_location
- 7q31 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Hereditary Papillary Renal Cell Carcinoma [NCIt concept]
gene_is_element_in_pathway
- Adherens Junction Assembly Pathway [NCIt concept]
- Adherens Junction Stabilization Pathway [NCIt concept]
- Alpha6/Beta1 and Alpha6/Beta4 Integrin Signaling Pathway [NCIt concept]
- AlphaM/Beta2 Integrin Signaling Pathway [NCIt concept]
- Axon Guidance Pathway [NCIt concept]
- Bacterial Invasion of Epithelial Cell Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- EGF Receptor Downregulation by CBL Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- Ephrin B Forward Signaling Pathway [NCIt concept]
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway BioCarta [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- Interferon-Gamma Signaling Pathway [NCIt concept]
- Malaria Pathway [NCIt concept]
- Melanoma Pathway [NCIt concept]
- Nectin Adhesion Pathway [NCIt concept]
- Neurotrophic Factor-Mediated NTRK1 Signaling Pathway [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- Regulation of Retinoblastoma Protein Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
- p38-alpha and p38-beta Signaling Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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