Serine/Threonine-Protein Kinase PAK 1

Preferred Label : Serine/Threonine-Protein Kinase PAK 1;

NCIt synonyms : AlphaPAK; EC 2.7.1.3; PAK-1; p65-PAK; p21-Activated Kinase 1; p21-Activated Kinase-1; PAK1;

NCIt definition : Serine/threonine-protein kinase PAK 1 (545 aa, 61 kDa) is encoded by the human PAK1 gene. This protein is involved in both protein phosphorylation and signal transduction.;

Details

Origin ID

C42594;

UMLS CUI

C1505379;

Currated CISMeF NLP mapping
- p21-Activated kinase 1 [MeSH concept]
OMIM relation
- P21 protein-activated kinase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PAK1 protein, human [MeSH concept]
- PAK1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- PAK1 Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Agrin Pathway [NCIt concept]
- Angiopoietin-1 Receptor Signaling Pathway [NCIt concept]
- Angiotensin II Signaling Pathway [NCIt concept]
- Aurora A Signaling Pathway [NCIt concept]
- Axon Guidance Pathway [NCIt concept]
- CXCR4-Mediated Signaling Pathway [NCIt concept]
- Cell Migration Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Ephrin A2 Forward Signaling Pathway [NCIt concept]
- Ephrin B Forward Signaling Pathway [NCIt concept]
- Epidermal Growth Factor Receptor Pathway [NCIt concept]
- Epithelial Cell Signaling Pathway in Helicobacter pylori Infection [NCIt concept]
- Fas Signaling Pathway BioCarta [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Formyl Peptide Receptor 1 Signaling Pathway [NCIt concept]
- G1 to S Transition Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- PDGFR-beta Signaling Pathway [NCIt concept]
- PLK1 Signaling Pathway [NCIt concept]
- Rac1 Cell Motility Signaling Pathway [NCIt concept]
- Ras-Independent Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
- Sphingosine 1-Phosphate Receptor 2 Signaling Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- TNFR1 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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