NCIt definition : Human CASP3 wild-type allele is located within 4q34 and is approximately 22 kb in
length. This allele, which encodes caspase-3 protein, is involved in the activation
of caspase-dependent apoptosis via proteolytic cleavage of poly (ADP-ribose) polymerase
as well as caspases 6, 7 and 9.;